Endocrinológiai Nem Önálló Tanszék

Mu endocrinology, BiosciAbstracts


    Fetuin-A is a hepatokine with a role in the regulation of mineralization, metabolism and the cardiovascular system.

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    Fetuin-A levels are known increased in obesity-linked diseases. To date, the role of fetuin-A in autoimmune thyroiditis has not been thoroughly investigated.

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    Subjects and methods In our study we investigated the association between thyroid hormone levels, thyroid antibodies, the components of lipid metabolism, anthropometrical parameters and fetuin-A. We mu endocrinology eighty-six patients 7 men, 79 women, mean age 43 ± 13 years, median BMI All patients had autoimmune thyroiditis with various thyroid hormone status from hypo- to hyperthyroidism. Thyroid hormone levels, anti-thyroperoxidase aTPO concentration and lipid parameters were measured by routine laboratory methods.

    Results Median serum fetuin-A level was Mean fT3 and fT4 were 4. However, we could not find correlation between fetuin-A and aTPO levels.

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    Conclusions The significant correlation between fetuin-A and fT3 levels might indicate a regulatory effect of T3 on metabolism. However, further clinical investigations are needed mu endocrinology clarify this relationship.

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    Volume 73 European Congress of Endocrinology Online.